Description

2-(6-Chloro-1H-Indol-1-Yl)-n-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound, with CAS number 1144460-80-9, is critical for medicinal chemists and process development teams working on novel therapeutic agents. It is primarily utilized in the synthesis of complex molecules targeting central nervous system (CNS) disorders and other specialized therapeutic areas.

Application

This specialized intermediate serves as a key building block in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical R&D: Core intermediate in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in early-stage drug discovery.
• Process Chemistry: Serves as a critical precursor in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Utilized in university and institutional labs for chemical biology and pharmacology studies.

Basic Information

Product Name	2-(6-Chloro-1H-Indol-1-Yl)-n-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Acetamide
CAS No.	1144460-80-9
Molecular Formula	C18H15ClN2O3
Molecular Weight	342.78 g/mol
Synonyms	2-(6-Chloro-1H-indol-1-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide; 2-(6-Chloro-1H-indol-1-yl)-N-(1,4-benzodioxan-6-yl)acetamide; 1144460-80-9; 2-(6-Chloroindol-1-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(6-chloro-1H-indol-1-yl)acetamide; 6-Chloro-1-[2-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]indole
EINECS	Contact for details

Quality Control

Our 2-(6-Chloro-1H-Indol-1-Yl)-n-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Acetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.