Description

2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile heterocyclic scaffold for creating new therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop next-generation products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Biochemical Research: Employed in academic and industrial research to study enzyme inhibition and receptor-ligand interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.

Basic Information

Product Name	2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide
CAS No.	1144455-72-0
Molecular Formula	C14H12ClN5OS
Molecular Weight	333.80 g/mol
Synonyms	2-(4-Chloro-1H-indol-1-yl)-N-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 2-(4-Chloro-1H-indol-1-yl)-N-[(2E)-5-ethyl-4,5-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide; 2-(4-Chloroindol-1-yl)-N-(5-ethyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide; (2E)-2-(4-Chloro-1H-indol-1-yl)-N-(5-ethyl-4,5-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide; Acetamide, 2-(4-chloro-1H-indol-1-yl)-N-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]-; CAS 1144455-72-0
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.