Description

2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development programs targeting new therapeutic agents, particularly in oncology and neurology. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel heterocyclic compounds with potential biological activity.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Serves as a precursor in the development of new Active Pharmaceutical Ingredients, especially those targeting kinase inhibition.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific enzyme interactions and pathways.
• Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) producing specialized compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and pharmacology.

Basic Information

Product Name	2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide
CAS No.	1144428-18-1
Molecular Formula	C15H14ClN5O2S
Molecular Weight	363.82 g/mol
Synonyms	2-(4-Chloro-1H-indol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 2-(4-Chloroindol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazolin-2-ylidene]acetamide; 1144428-18-1; Acetamide, 2-(4-chloro-1H-indol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]-; (2E)-2-(4-Chloro-1H-indol-1-yl)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.