Description

(1-Methyl-1H-Indazol-4-Yl)Methanamine is a high-purity, functionalized indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel small molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and medicinal chemistry programs, particularly those targeting kinase inhibition and other protein-ligand interactions.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Scaffold: Used as a core structure for designing and synthesizing compound libraries for high-throughput screening (HTS).
• Kinase Inhibitor Development: The indazole moiety is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery projects.
• Academic Research: Used in universities and institutes for fundamental studies in heterocyclic chemistry and bioorganic synthesis.

Basic Information

Product Name	(1-Methyl-1H-Indazol-4-Yl)Methanamine
CAS No.	1144044-68-7
Molecular Formula	C9H11N3
Molecular Weight	161.21 g/mol
Synonyms	4-(Aminomethyl)-1-methyl-1H-indazole; 1-Methyl-1H-indazole-4-methanamine; (1-Methylindazol-4-yl)methanamine; 1-Methyl-4-(aminomethyl)-1H-indazole; 4-(Aminomethyl)-1-methylindazole; 1-Methyl-4-indazolemethanamine; 1144044-68-7
EINECS	Contact for details

Quality Control

Our (1-Methyl-1H-Indazol-4-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports cGMP and ISO standards as required for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.