Description

(R)-2-(Bromomethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine is a high-value chiral building block and key synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in the reactive bromomethyl group attached to a chiral benzodioxane scaffold, enabling precise stereochemical control in the construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring specific enantiomeric purity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, especially for central nervous system (CNS) agents, adrenergic receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of chiral monomers for advanced polymers and functional materials with specific optical properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and receptor interactions where stereochemistry is crucial.

Basic Information

Product Name	(R)-2-(Bromomethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine
CAS No.	1142953-55-6
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	(R)-2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine; (R)-2-Bromomethyl-1,4-benzodioxane; (R)-2,3-Dihydro-2-(bromomethyl)-1,4-benzodioxin; (R)-1,4-Benzodioxan-2-ylmethyl bromide; (R)-Benzodioxane-2-methyl bromide; (R)-BDBMBr; (R)-Enantiomer of 2-(Bromomethyl)-2,3-dihydrobenzo[b][1,4]dioxine
EINECS	Contact for details

Quality Control

Our (R)-2-(Bromomethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including Chiral HPLC, NMR, and GC/MS to confirm identity, chemical purity, and enantiomeric excess (ee). Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and scale-up with custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.