Description

3,5-Dimethyl-4-Hydroxybenzonitrile-D8 is a deuterated isotopologue of the phenolic compound 3,5-dimethyl-4-hydroxybenzonitrile. This stable isotope-labeled compound is essential as an internal standard in quantitative mass spectrometry, enabling precise and accurate analytical measurements. It is primarily required by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS analysis in bioanalytical studies.
• Quantitative reference standard in pharmaceutical research and development.
• Metabolite quantification and pharmacokinetic (PK) profiling.
• Use in environmental analysis for tracing specific phenolic derivatives.
• Stable isotope dilution analysis in complex biological matrices.
• Method validation and quality control in analytical laboratories.

Basic Information

Product Name	3,5-Dimethyl-4-Hydroxybenzonitrile-D8
CAS No.	1142096-16-9
Molecular Formula	C9H1D8NO
Molecular Weight	152.23 g/mol (approx.)
Synonyms	4-Hydroxy-3,5-dimethylbenzonitrile-d8; 3,5-Dimethyl-4-hydroxybenzonitrile (deuterated); 4-Cyano-2,6-dimethylphenol-d8; Deuterated Cyanox; D8-3,5-Dimethyl-4-hydroxybenzonitrile; 4-Hydroxy-3,5-dimethylbenzonitrile (phenyl-d8)
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under stringent conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes comprehensive analysis, including NMR and mass spectrometry, to confirm deuteration level and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (e.g., D8 > 98 atom % D), chemical purity (by HPLC), and analytical data are provided to guarantee consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D (D8)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.