Description

4-(2-Nitrophenyl)-1,3-Thiazole-2-Carboxylic Acid is a specialized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors or other small molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique thiazole-nitrophenyl structure.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including amide coupling, esterification, or reduction reactions to create diverse chemical libraries.
• Material Science Research: Potential use in the synthesis of organic electronic materials or ligands for metal-organic frameworks (MOFs) due to its conjugated system and coordinating carboxylic acid group.
• Chemical Biology Probe Development: Can be utilized to create molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	4-(2-Nitrophenyl)-1,3-Thiazole-2-Carboxylic Acid
CAS No.	1141669-77-3
Molecular Formula	C10H6N2O4S
Molecular Weight	250.23 g/mol
Synonyms	2-(2-Nitrophenyl)thiazole-4-carboxylic acid; 4-(2-Nitrophenyl)-1,3-thiazole-2-carboxylic acid; 2-Carboxy-4-(2-nitrophenyl)thiazole; 4-(o-Nitrophenyl)thiazole-2-carboxylic acid; 2-Thiazolecarboxylic acid, 4-(2-nitrophenyl)-; 1141669-77-3; 4-(2-Nitrophenyl)-2-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Nitrophenyl)-1,3-Thiazole-2-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consideration should be given to maintaining an inert atmosphere (e.g., under nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.