Description

3-Mercaptopropionic-2,2,3,3-D4 Acid is a deuterium-labeled isotopologue of 3-mercaptopropionic acid, a critical building block and analytical standard. This compound is essential for applications requiring precise molecular tracking, such as metabolic pathway studies and the development of stable isotope-labeled pharmaceuticals. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for its utility in mass spectrometry, NMR spectroscopy, and as a tracer in chemical synthesis.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of 3-mercaptopropionic acid and related metabolites in biological matrices via LC-MS or GC-MS.
• Use in deuterium-labeling studies to investigate reaction mechanisms, pharmacokinetics, and metabolic pathways in pharmaceutical research.
• As a specialized monomer or intermediate in the synthesis of deuterated polymers and advanced materials where specific isotopic content is required.
• For the preparation of isotopically labeled catalysts or ligands to study catalytic processes and surface interactions.
• In NMR spectroscopy as a chemical shift reference or to simplify complex spectra by replacing protons with deuterons.
• As a high-purity reagent in the development and quality control of deuterated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Mercaptopropionic-2,2,3,3-D4 Acid
CAS No.	1141488-67-6
Molecular Formula	C3D4H2O2S
Molecular Weight	110.16 g/mol
Synonyms	3-Mercaptopropionic-d4 Acid; β-Mercaptopropionic-2,2,3,3-d4 Acid; 3-Thiopropionic-2,2,3,3-d4 Acid; Deuterated 3-Mercaptopropanoic Acid; [2,2,3,3-2H4]-3-Mercaptopropionic Acid; 3-MPA-d4; DL-3-Mercaptopropionic-2,2,3,3-d4 Acid; 3-Sulfanylpropanoic-2,2,3,3-d4 Acid
EINECS	Contact for details

Quality Control

Our 3-Mercaptopropionic-2,2,3,3-D4 Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to ensure high isotopic purity and chemical purity. Certificates of Analysis (COA) detailing the isotopic enrichment, chemical assay, and impurity profile are provided to guarantee consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its properties as a strong acid/organic solvent and being easily oxidized, prolonged exposure to air, moisture, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.