Description

4-Bromo-2-(Bromomethyl)Thiazole is a high-purity, multi-functional brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual reactive sites, which enable efficient derivatization and the construction of complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of new generation fungicides and herbicides, leveraging the thiazole core for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials due to its halogenated structure.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and inhibitors to study biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services to global clients.

Basic Information

Product Name	4-Bromo-2-(Bromomethyl)Thiazole
CAS No.	1138333-26-2
Molecular Formula	C4H3Br2NS
Molecular Weight	256.95 g/mol
Synonyms	2-(Bromomethyl)-4-bromothiazole; 4-Bromo-2-bromomethylthiazole; Thiazole, 4-bromo-2-(bromomethyl)-; 2,4-Dibromomethylthiazole (common misnomer); 1138333-26-2; 4-Bromo-2-(bromanyl-methyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Bromomethyl)Thiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.