Description

tert-Butyl 2-((1R,5S,6S)-6-(((tert-Butoxycarbonyl)Amino)Methyl)-3-Ethylbicyclo[3.2.0]Hept-3-En-6-Yl)Acetate CAS NO 1138246-20-4 is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic scaffold with orthogonal protecting groups. This compound matters as a critical building block in the synthesis of novel, structurally complex active pharmaceutical ingredients (APIs), enabling precise stereochemical control. It is primarily needed by research organizations and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations essential for biological activity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.

Basic Information

Product Name	tert-Butyl 2-((1R,5S,6S)-6-(((tert-Butoxycarbonyl)Amino)Methyl)-3-Ethylbicyclo[3.2.0]Hept-3-En-6-Yl)Acetate
CAS No.	1138246-20-4
Molecular Formula	C22H37NO4
Molecular Weight	379.54 g/mol
Synonyms	1,1-Dimethylethyl (1R,5S,6S)-6-[[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]-3-ethylbicyclo[3.2.0]hept-3-ene-6-acetate; BOC-Protected Bicyclo[3.2.0]heptene Intermediate; tert-Butyl (1R,5S,6S)-6-[(tert-Butoxycarbonylamino)methyl]-3-ethylbicyclo[3.2.0]hept-3-ene-6-acetate; (1R,5S,6S)-6-((((tert-Butoxy)carbonyl)amino)methyl)-3-ethylbicyclo[3.2.0]hept-3-ene-6-acetic acid tert-butyl ester; Bicyclo[3.2.0]heptene Derivative, BOC-Amino Methyl Ethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-((1R,5S,6S)-6-(((tert-Butoxycarbonyl)Amino)Methyl)-3-Ethylbicyclo[3.2.0]Hept-3-En-6-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.