Description

2-Chloro-5-(Piperazin-1-Ylmethyl)Thiazole is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. Its molecular architecture, featuring both a thiazole and a piperazine moiety, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a building block for specialty polymers and functional materials with specific electronic or binding properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	2-Chloro-5-(Piperazin-1-Ylmethyl)Thiazole
CAS No.	1135439-05-2
Molecular Formula	C8H12ClN3S
Molecular Weight	217.72 g/mol
Synonyms	2-Chloro-5-(piperazin-1-ylmethyl)thiazole; 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperazine; 2-Chloro-5-(piperazin-1-ylmethyl)-1,3-thiazole; 1135439-05-2; 2-Chloro-5-piperazin-1-ylmethyl-thiazole; 5-(Piperazin-1-ylmethyl)-2-chlorothiazole; 2-Chloro-5-(1-piperazinylmethyl)thiazole
EINECS	Contact for details

Quality Control

We maintain a strict quality management system aligned with cGMP principles for pharmaceutical intermediates. Every batch of 2-Chloro-5-(Piperazin-1-Ylmethyl)Thiazole is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.