Description

3-Iodo-4-Methylthiophene-2-Carboxylic Acid Potassium Salt is a high-purity, organosulfur building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures, particularly in heterocyclic chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel thiophene-based drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides that leverage the thiophene scaffold for enhanced activity.
• Material Science: Serves as a precursor for functionalized monomers in conductive polymers or organic semiconductors (OLEDs, OFETs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Ligand Synthesis: Utilized for creating novel sulfur-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Acts as a probe or labeling agent in bioconjugation chemistry due to its reactive halogen and carboxylic acid salt functionality.

Basic Information

Product Name	3-Iodo-4-Methylthiophene-2-Carboxylic Acid Potassium Salt
CAS No.	1135387-78-8
Molecular Formula	C7H4IKO2S
Molecular Weight	318.17 g/mol
Synonyms	Potassium 3-Iodo-4-methylthiophene-2-carboxylate; 4-Methyl-3-iodothiophene-2-carboxylic Acid Potassium Salt; 2-Thiophenecarboxylic acid, 3-iodo-4-methyl-, potassium salt; 3-Iodo-4-methyl-2-thiophenecarboxylic acid potassium salt
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methylthiophene-2-Carboxylic Acid Potassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.