Description

5-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in the unique reactivity of the aldehyde group and the electron-withdrawing trifluoromethyl substituent, which are critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs), especially those targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated benzothiophene core.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable substrate for further functionalization in fluorine chemistry, enabling the introduction of complex fluorinated motifs.

Basic Information

Product Name	5-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde
CAS No.	1135283-83-8
Molecular Formula	C10H5F3OS
Molecular Weight	230.21 g/mol
Synonyms	5-(Trifluoromethyl)benzo[b]thiophene-2-carboxaldehyde; 1-Benzothiophene-2-carboxaldehyde, 5-(trifluoromethyl)-; 5-Trifluoromethyl-1-benzothiophene-2-carbaldehyde; 5-Trifluoromethylbenzo[b]thiophene-2-carbaldehyde; 2-Formyl-5-(trifluoromethyl)benzothiophene
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.