Description

1-(tert-Butyl) 2-Ethyl 3-Bromo-1H-Indole-1,2-Dicarboxylate is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a critical protected intermediate for the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel indole-based scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with indole core structures.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Stille) and further functionalization due to the reactive bromine atom.
• Material Science: Intermediate in the production of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	1-(tert-Butyl) 2-Ethyl 3-Bromo-1H-Indole-1,2-Dicarboxylate
CAS No.	1135283-20-3
Molecular Formula	C₁₇H₂₀BrNO₄
Molecular Weight	382.25 g/mol
Synonyms	3-Bromo-1H-indole-1,2-dicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester; 1-tert-Butyl 2-ethyl 3-bromo-1H-indole-1,2-dicarboxylate; tert-Butyl ethyl 3-bromoindole-1,2-dicarboxylate; 3-Bromoindole-1,2-dicarboxylic acid tert-butyl ethyl diester; Ethyl 1-(tert-butoxycarbonyl)-3-bromo-1H-indole-2-carboxylate; Boc-protected 3-bromoindole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-(tert-Butyl) 2-Ethyl 3-Bromo-1H-Indole-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.