Description

Methyl 3-(2-Hydroxyethyl)-1H-Indole-5-Carboxylate is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylate ester and a hydroxyethyl side chain, makes it a versatile intermediate for constructing complex pharmacophores and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

This specialized indole ester is a key synthetic intermediate with applications across several high-value industries:

• Pharmaceutical Intermediates: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in neurological and oncological research.
• Agrochemical Synthesis: Used in the development of new-generation plant growth regulators and protective agents.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport or emissive layer materials in advanced display technologies.
• Ligand and Catalyst Development: Functionalized to create novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probes and Dyes: Utilized in the synthesis of indole-based fluorophores for bio-imaging and sensor applications.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	Methyl 3-(2-Hydroxyethyl)-1H-Indole-5-Carboxylate
CAS No.	1135272-67-1
Molecular Formula	C₁₂H₁₃NO₃
Molecular Weight	219.24 g/mol
Synonyms	5-Carbomethoxy-3-(2-hydroxyethyl)indole; Methyl 5-indolecarboxylate, 3-(2-hydroxyethyl)-; 3-(2-Hydroxyethyl)-1H-indole-5-carboxylic acid methyl ester; 1H-Indole-5-carboxylic acid, 3-(2-hydroxyethyl)-, methyl ester; 3-(2-Hydroxyethyl)indole-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(2-Hydroxyethyl)-1H-Indole-5-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.