Description

6-tert-Butyl 2-Ethyl 4,5-Dihydrothieno[2,3-C]Pyridine-2,6(7H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1135124-02-5. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its specific heterocyclic structure that enables precise molecular modifications. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex fused-ring heterocyclic systems.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Development & Scale-Up: Serves as a critical raw material for process chemists during the optimization and kilogram-scale production of APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's drug discovery and development pipelines.

Basic Information

Product Name	6-tert-Butyl 2-Ethyl 4,5-Dihydrothieno[2,3-C]Pyridine-2,6(7H)-Dicarboxylate
CAS No.	1135124-02-5
Molecular Formula	C15H21NO4S
Molecular Weight	311.40 g/mol
Synonyms	6-tert-Butyl 2-ethyl 4,7-dihydrothieno[2,3-c]pyridine-2,6(5H)-dicarboxylate; 2-Ethyl 6-tert-butyl 4,5-dihydrothieno[2,3-c]pyridine-2,6(7H)-dicarboxylate; Thieno[2,3-c]pyridine-2,6-dicarboxylic acid, 4,5-dihydro-, 2-ethyl 6-(1,1-dimethylethyl) ester; 1135124-02-5; tert-Butyl 2-ethyl 4,7-dihydro-5H-thieno[2,3-c]pyridine-2,6-dicarboxylate
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl 2-Ethyl 4,5-Dihydrothieno[2,3-C]Pyridine-2,6(7H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong alkalis and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.