Description

2-Chloro-1-(5-Ethoxy-1H-Indol-3-Yl)Ethanone is a specialized indole derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize complex heterocyclic compounds targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those with indole-based scaffolds.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides with specific biological activity.
• Biochemical Probe Development: Utilized in creating molecular tools for studying biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for advanced organic electronic materials and functional polymers.

Basic Information

Product Name	2-Chloro-1-(5-Ethoxy-1H-Indol-3-Yl)Ethanone
CAS No.	1134334-66-9
Molecular Formula	C₁₂H₁₂ClNO₂
Molecular Weight	237.68 g/mol
Synonyms	2-Chloro-1-(5-ethoxy-1H-indol-3-yl)ethanone; 3-Acetyl-5-ethoxyindole Hydrochloride (related salt); 5-Ethoxy-3-(2-chloroacetyl)indole; 1-(5-Ethoxy-1H-indol-3-yl)-2-chloroethanone; 2-Chloro-1-(5-ethoxyindol-3-yl)ethanone; α-Chloro-5-ethoxy-3-indolyl methyl ketone; 3-(2-Chloroacetyl)-5-ethoxyindole
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(5-Ethoxy-1H-Indol-3-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity verification. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.