Description

2-Chloro-1-(1,2,5-Trimethyl-1H-Indol-3-Yl)Ethanone is a specialized indole-based ketone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules, particularly in the development of novel heterocyclic compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and explore structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indole-based drug candidates, including potential receptor modulators and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold for biological activity.
• Organic Synthesis: Serves as a versatile electrophile or functionalized precursor in complex multi-step synthesis for academic and industrial R&D.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors, dyes, and photochromic materials due to its conjugated indole system.
• Chemical Biology Probe Development: Utilized to create molecular probes and labeled compounds for studying biological pathways and target engagement.

Basic Information

Product Name	2-Chloro-1-(1,2,5-Trimethyl-1H-Indol-3-Yl)Ethanone
CAS No.	1134334-65-8
Molecular Formula	C₁₃H₁₄ClNO
Molecular Weight	235.71 g/mol
Synonyms	2-Chloro-1-(1,2,5-trimethyl-1H-indol-3-yl)ethan-1-one; 3-Acetyl-1,2,5-trimethylindole, 2-chloro derivative; 1-(1,2,5-Trimethyl-1H-indol-3-yl)-2-chloroethanone; 2-Chloro-1-(1,2,5-trimethylindol-3-yl)ethanone; α-Chloro-1,2,5-trimethyl-3-indolyl ketone; 1134334-65-8; 2-Chloro-1-(1,2,5-trimethylindol-3-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and batch-to-batch consistency. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is available upon request. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical research, ensuring traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.