Description

5-(6-Methyl-1H-Indol-3-Yl)-1,3-Thiazol-2-Amine is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This specialized intermediate is valued for its unique indole-thiazole hybrid structure, which is essential for developing novel compounds with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new chemical entities (NCEs) for drug discovery, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Serves as a reference standard or probe molecule in biochemical and pharmacological assays to investigate specific biological pathways.
• Agrochemical Development: Potential application as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for fundamental organic synthesis and heterocyclic chemistry projects.
• Material Science Research: Investigated as a potential monomer or functional unit for creating advanced organic electronic materials or polymers.

Basic Information

Product Name	5-(6-Methyl-1H-Indol-3-Yl)-1,3-Thiazol-2-Amine
CAS No.	1134334-49-8
Molecular Formula	C₁₂H₁₁N₃S
Molecular Weight	229.30 g/mol
Synonyms	5-(6-Methyl-1H-indol-3-yl)-1,3-thiazol-2-amine; 2-Amino-5-(6-methyl-1H-indol-3-yl)thiazole; 5-(6-Methylindol-3-yl)thiazol-2-amine; 1134334-49-8; 5-(6-Methyl-1H-indol-3-yl)-2-aminothiazole; 2-Thiazolamine, 5-(6-methyl-1H-indol-3-yl)-; 5-(6-Methyl-1H-indol-3-yl)-1,3-thiazol-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-(6-Methyl-1H-Indol-3-Yl)-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.