Description

4-Oxo-3,4-Dihydro-1H-Isoquinoline-2-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering significant value in medicinal chemistry for its structural versatility. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel pesticides and herbicides.
• Chemical Biology: Serves as a probe or building block for the development of enzyme inhibitors and other biologically active molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	4-Oxo-3,4-Dihydro-1H-Isoquinoline-2-Carboxylic Acid tert-Butyl Ester
CAS No.	1134327-89-1
Molecular Formula	C14H15NO3
Molecular Weight	245.27 g/mol
Synonyms	tert-Butyl 4-oxo-3,4-dihydro-1H-isoquinoline-2-carboxylate; 1H-Isoquinoline-2-carboxylic acid, 3,4-dihydro-4-oxo-, 1,1-dimethylethyl ester; 4-Oxo-1,4-dihydro-isoquinoline-2-carboxylic acid tert-butyl ester; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-4-one; BOC-protected 4-oxo-3,4-dihydroisoquinoline; 4-Oxo-3,4-dihydroisoquinoline-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-Oxo-3,4-Dihydro-1H-Isoquinoline-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.