Description

B-[4-Methyl-3-[[4-(2-Pyridinylmethoxy)Benzoyl]Amino]Phenyl]Boronic Acid is a sophisticated boronic acid derivative designed for advanced synthetic and pharmaceutical research. This compound is a critical building block in modern organic synthesis, particularly valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: An essential reagent for forming carbon-carbon bonds between aryl or vinyl boronic acids and halides, enabling the construction of biaryl and other complex structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-boronic acid motifs.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes targeting proteins or enzymes.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	B-[4-Methyl-3-[[4-(2-Pyridinylmethoxy)Benzoyl]Amino]Phenyl]Boronic Acid
CAS No.	1126369-28-5
Molecular Formula	C20H19BN2O3
Molecular Weight	346.19 g/mol
Synonyms	4-Methyl-3-[[4-(2-pyridinylmethoxy)benzoyl]amino]benzeneboronic Acid; (3-((4-((Pyridin-2-ylmethoxy)benzamido))-4-methylphenyl)boronic Acid; 2-Pyridinemethanol, 4-[[(3-borono-4-methylphenyl)amino]carbonyl]phenyl ether; B-[4-Methyl-3-[[4-(2-Pyridylmethoxy)Benzoyl]Amino]Phenyl]Boronic Acid; 1126369-28-5; UNII-9F8F8V2Q0K
EINECS	Contact for details

Quality Control

Our B-[4-Methyl-3-[[4-(2-Pyridinylmethoxy)Benzoyl]Amino]Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.