Description

2,4-Difluoro-α-(1H-1,2,4-Triazolyl)Acetophenone-D2 is a deuterated aromatic ketone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in the preparation of isotopically labeled molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for drug discovery, metabolic studies, and the synthesis of novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing deuterated drug candidates, enhancing metabolic stability and enabling pharmacokinetic studies.
• Agrochemical Research: Used in the development of novel, isotopically labeled fungicides and pesticides, particularly those containing triazole moieties.
• Metabolic Pathway Tracing: Acts as a precursor for compounds used in mass spectrometry and NMR-based metabolic research.
• Organic Synthesis: Serves as a versatile intermediate for introducing the difluorophenyl and triazolyl groups into complex molecular architectures.
• Isotope Labeling Services: Supplied to contract research organizations (CROs) and CDMOs specializing in the production of deuterated compounds.
• Material Science: Potential intermediate for creating specialty polymers or ligands with specific electronic properties.

Basic Information

Product Name	2,4-Difluoro-α-(1H-1,2,4-Triazolyl)Acetophenone-D2
CAS No.	1124197-63-2
Molecular Formula	C10H5D2F2N3O
Molecular Weight	225.19 g/mol
Synonyms	2,4-Difluoro-α-(1H-1,2,4-triazol-1-yl)acetophenone-d2; 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone-d2; Deuterated 2,4-Difluoro-α-(1,2,4-triazol-1-yl)acetophenone; α-(1H-1,2,4-Triazol-1-yl)-2,4-difluoroacetophenone-d2; 2,4-DFTA-D2; 1124197-63-2
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-α-(1H-1,2,4-Triazolyl)Acetophenone-D2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F) and HPLC, to confirm identity, chemical purity, and isotopic enrichment. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.