Description

6-Methoxy-Benzo[D]Isothiazole-3-Carboxylic Acid Methyl Ester is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic scaffolds found in active pharmaceutical ingredients and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactive isothiazole core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tags to study enzyme function and protein interactions.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	6-Methoxy-Benzo[D]Isothiazole-3-Carboxylic Acid Methyl Ester
CAS No.	1123169-11-8
Molecular Formula	C10H9NO3S
Molecular Weight	223.25 g/mol
Synonyms	Methyl 6-Methoxybenzo[d]isothiazole-3-carboxylate; 6-Methoxy-1,2-benzisothiazole-3-carboxylic Acid Methyl Ester; 6-Methoxybenzoisothiazole-3-carboxylic Acid Methyl Ester; 6-Methoxybenzisothiazole-3-carboxylic Acid Methyl Ester; 1123169-11-8; Methyl 6-methoxy-1,2-benzisothiazole-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 6-Methoxy-Benzo[D]Isothiazole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.