Description

1-Cyclopropyl-1,3-Benzodiazole-5-Carbonitrile is a high-value, heterocyclic organic compound featuring a benzodiazole core functionalized with a cyclopropyl and a nitrile group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Organic Synthesis Building Block: The reactive nitrile and fused diazole ring system are utilized in cyclization, coupling, and functional group transformation reactions to create complex heterocycles.
• Material Science Precursor: Used in research for developing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in academic and industrial research to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Cyclopropyl-1,3-Benzodiazole-5-Carbonitrile
CAS No.	1120244-55-4
Molecular Formula	C11H9N3
Molecular Weight	183.21 g/mol
Synonyms	5-Cyano-1-cyclopropyl-1H-benzimidazole; 1-Cyclopropyl-1H-benzimidazole-5-carbonitrile; 1-Cyclopropyl-5-cyanobenzimidazole; 1H-Benzimidazole-5-carbonitrile, 1-cyclopropyl-; Benzimidazole-5-carbonitrile, 1-cyclopropyl-; 1-Cyclopropylbenzimidazole-5-carbonitrile; 1120244-55-4; 5-CN-1-Cyclopropylbenzimidazole
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1,3-Benzodiazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development and commercial projects with material produced under current Good Manufacturing Practice (cGMP) guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.