Description

2-(2-Bromobutanoyl)-1,2,3,4-Tetrahydroisoquinoline is a specialized brominated tetrahydroisoquinoline derivative, a key advanced intermediate in modern organic synthesis. This compound matters for its role as a versatile building block in constructing complex nitrogen-containing heterocycles, which are prevalent in active pharmaceutical ingredients. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules and for process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly those containing the tetrahydroisoquinoline pharmacophore.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its reactive bromine and ketone functionalities.
• Organic Synthesis Reagent: Serves as a versatile precursor in multi-step synthesis for constructing complex molecular architectures in academic and industrial R&D.
• Chemical Biology Probe Development: Employed in the creation of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials with unique electronic properties.

Basic Information

Product Name	2-(2-Bromobutanoyl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1119453-05-2
Molecular Formula	C₁₃H₁₄BrNO
Molecular Weight	280.16 g/mol
Synonyms	2-(2-Bromobutanoyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(2-bromo-1-oxobutyl)isoquinoline; 2-(2-Bromobutyryl)-1,2,3,4-tetrahydroisoquinoline; 2-(2-Bromo-1-oxobutyl)-1,2,3,4-tetrahydroisoquinoline; 2-(α-Bromobutyryl)-1,2,3,4-tetrahydroisoquinoline; 2-(2-Bromopropanoyl)-1,2,3,4-tetrahydroisoquinoline (common misnomer); Brominated THIQ derivative; BBTIQ
EINECS	Contact for details

Quality Control

Our 2-(2-Bromobutanoyl)-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.