Description

8-Oxo-5,8,13,13A-Tetrahydro-6H-Isoquino[3,2-A]Isoquinoline-13-Carboxylic Acid is a high-purity, complex heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical candidates and sophisticated chemical entities. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex alkaloid-like structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new active pharmaceutical ingredients (APIs).
• Organic Synthesis: Serves as a versatile precursor for constructing complex polycyclic frameworks and alkaloid analogs in academic and industrial research.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for advanced chemical products.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Oxo-5,8,13,13A-Tetrahydro-6H-Isoquino[3,2-A]Isoquinoline-13-Carboxylic Acid
CAS No.	1119452-84-4
Molecular Formula	C₁₇H₁₃NO₃
Molecular Weight	279.29 g/mol
Synonyms	8-Oxo-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-13-carboxylic acid; 13-Carboxy-5,8,13,13a-tetrahydro-8-oxo-6H-isoquino[3,2-a]isoquinoline; 1119452-84-4; Isoquino[3,2-a]isoquinoline-13-carboxylic acid, 5,8,13,13a-tetrahydro-8-oxo-; Tetrahydroisoquinoisoquinolinecarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 8-Oxo-5,8,13,13A-Tetrahydro-6H-Isoquino[3,2-A]Isoquinoline-13-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.