Description

3-(1H-Indol-3-Yl)-2-(2-Methoxyethyl)-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and neurology. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Oncology Drug Development: Employed in the research of potential kinase inhibitors and other targeted cancer therapies due to its fused isoquinoline-indole structure.
• Neurological Disorder Research: Investigated for applications in developing compounds for central nervous system (CNS) disorders.
• Biochemical Tool Compound: Acts as a reference standard or probe in biochemical assays to study enzyme inhibition and receptor binding.
• Custom Synthesis Building Block: Provided to fine chemical companies for the custom manufacturing of specialized compounds for client-specific research programs.

Basic Information

Product Name	3-(1H-Indol-3-Yl)-2-(2-Methoxyethyl)-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid
CAS No.	1119449-96-5
Molecular Formula	C21H18N2O4
Molecular Weight	362.38 g/mol
Synonyms	3-(1H-Indol-3-yl)-2-(2-methoxyethyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid; 2-(2-Methoxyethyl)-3-(1H-indol-3-yl)-1-oxo-1,2-dihydro-4-isoquinolinecarboxylic Acid; 1,2-Dihydro-2-(2-methoxyethyl)-3-(1H-indol-3-yl)-1-oxo-4-isoquinolinecarboxylic Acid; 4-Isoquinolinecarboxylic acid, 1,2-dihydro-2-(2-methoxyethyl)-3-(1H-indol-3-yl)-1-oxo-; UNII-6T0I6L6T4Y; 6T0I6L6T4Y; CHEMBL3186582
EINECS	Contact for details

Quality Control

Our 3-(1H-Indol-3-Yl)-2-(2-Methoxyethyl)-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under conditions that minimize exposure to light and atmospheric moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.