Description

6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a defined chiral center and functional groups for targeted molecular construction. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly within the central nervous system (CNS) and oncology drug pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel drug candidates.
• Neurological Drug Development: Serves as a core structural motif for potential treatments targeting neurological disorders.
• Oncological Research: Used in the construction of experimental compounds for cancer therapy research.
• Chemical Biology: Employed as a scaffold or probe in the study of enzyme inhibition and receptor binding.
• Process Chemistry: Utilized in route scouting and scale-up optimization for API manufacturing.
• Academic Research: A valuable compound for synthetic organic chemistry studies and methodology development.

Basic Information

Product Name	6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Amine
CAS No.	1116230-89-7
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	7-Amino-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-6-methoxy-3,4-dihydro-1H-isoquinolin-7-amine; 6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine; 7-Amino-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-6-methoxy-2-methyl-7-isoquinolinamine; 6-Methoxy-2-methyl-7-amino-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.