Description

7-Methoxy-3-Nitro-4-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its specific azaindole scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel kinase inhibitors and other targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic programs.
• Chemical Biology Probes: Serves as a core structure for developing selective enzyme inhibitors used as research tools.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the methoxy-nitro-azaindole moiety into larger molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	7-Methoxy-3-Nitro-4-Azaindole
CAS No.	1116136-57-2
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	3-Nitro-7-methoxy-1H-pyrrolo[2,3-b]pyridine; 7-Methoxy-3-nitro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 7-methoxy-3-nitro-; 4-Azaindole, 7-methoxy-3-nitro-; 3-Nitro-7-methoxy-4-azaindole; 7-Methoxy-3-nitro-4-aza-indole; 7-Methoxy-3-nitropyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 7-Methoxy-3-Nitro-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.