Description

2-[(4-Ethyl-5-Methyl-4H-1,2,4-Triazol-3-Yl)Thio]Ethanamine(Saltdata: 2Hbr) is a high-purity, functionalized triazole derivative offered as a hydrobromide salt for enhanced stability and handling. This compound is a critical pharmaceutical intermediate and organic building block valued for its unique heterocyclic structure, which is integral to developing novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new fungicides, herbicides, and plant growth regulators due to the bioactivity of the 1,2,4-triazole moiety.
• Ligand Synthesis in Catalysis: Used to create specialized ligands for transition metal catalysts, enhancing efficiency in cross-coupling and other organic transformations.
• Material Science: Employed in the development of advanced polymers and functional materials where the triazole ring contributes to thermal stability and specific electronic properties.
• Bioconjugation & Probe Development: The reactive thioether and amine functionalities make it suitable for creating chemical probes and bioconjugates for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial R&D laboratories.

Basic Information

Product Name	2-[(4-Ethyl-5-Methyl-4H-1,2,4-Triazol-3-Yl)Thio]Ethanamine(Saltdata: 2Hbr)
CAS No.	1114597-94-2
Molecular Formula	C7H14N4S • 2HBr
Molecular Weight	362.05 g/mol (for salt form)
Synonyms	2-[(4-Ethyl-5-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]ethan-1-amine dihydrobromide; 2-((4-Ethyl-5-methyl-4H-1,2,4-triazol-3-yl)thio)ethanamine hydrobromide (2:1); 2-[(4-Ethyl-5-methyl-1,2,4-triazol-3-yl)thio]ethylamine dihydrobromide; AE-MTZTA 2HBr; 1114597-94-2 (CAS); Triazole-thio-ethylamine HBr salt
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Ethyl-5-Methyl-4H-1,2,4-Triazol-3-Yl)Thio]Ethanamine(Saltdata: 2Hbr) is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.