Description

3-(2-(tert-Butoxy)-2-Oxoethyl)Bicyclo[1.1.1]Pentane-1-Carboxylicacid is a high-value, synthetically challenging bicyclic building block featuring a unique [1.1.1]propellane core. This compound matters as a critical intermediate for medicinal chemistry and advanced materials research, enabling the synthesis of novel, three-dimensional molecular architectures with improved physicochemical properties. Pharmaceutical and agrochemical R&D teams need it to develop new active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets, leveraging its three-dimensional structure to escape flatland.
• Agrochemical Research: Used to create advanced active ingredients with improved environmental and metabolic profiles for crop protection.
• Materials Science: Building block for developing specialty polymers and advanced organic frameworks with unique mechanical or optical properties.
• Chemical Biology: Employed as a probe or linker in proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules due to its rigid, bioisosteric nature.
• Academic & Industrial R&D: Serves as a valuable reagent for methodology development and exploring new chemical space in organic synthesis.

Basic Information

Product Name	3-(2-(tert-Butoxy)-2-Oxoethyl)Bicyclo[1.1.1]Pentane-1-Carboxylicacid
CAS No.	1113001-76-5
Molecular Formula	C13H20O4
Molecular Weight	240.30 g/mol
Synonyms	3-[2-(tert-Butoxy)-2-oxoethyl]bicyclo[1.1.1]pentane-1-carboxylic acid; 1,3-Disubstituted [1.1.1]Propellane Derivative; tert-Butyl 2-(3-carboxybicyclo[1.1.1]pentan-1-yl)acetate; BCP-COOH Ester Derivative; Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-(2-((1,1-dimethylethoxy)carbonyl)ethyl)-; T-butyl 2-(3-carboxy-1-bicyclo[1.1.1]pentanyl)acetate
EINECS	Contact for details

Quality Control

Our production of 3-(2-(tert-Butoxy)-2-Oxoethyl)Bicyclo[1.1.1]Pentane-1-Carboxylicacid adheres to stringent quality protocols suitable for research and development applications. Every batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.