Description

5-Bromoisoquinoline-1-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and carboxylic acid functional groups, enabling precise molecular construction in complex chemical environments. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its isoquinoline core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of advanced organic electronic materials and dyes.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig couplings.
• Peptidomimetic Chemistry: The carboxylic acid group allows for incorporation into peptide-like structures for medicinal chemistry applications.

Basic Information

Product Name	5-Bromoisoquinoline-1-Carboxylic Acid
CAS No.	1111311-65-9
Molecular Formula	C10H6BrNO2
Molecular Weight	252.07 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 5-bromo-; 5-Bromo-1-isoquinolinecarboxylic acid; 5-Bromoisoquinoline-1-carboxylic acid; 1-Carboxy-5-bromoisoquinoline; 5-Bromo-1-carboxyisoquinoline; 1111311-65-9; 5-Br-IQC-OH
EINECS	Contact for details

Quality Control

Our 5-Bromoisoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.