Description

Boronic Acid, B-(5-Methoxy[1,1'-Biphenyl]-3-Yl)- is a high-purity, biphenyl-substituted boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who require precise and reliable intermediates for drug discovery and organic electronic development. Its specific structure offers unique steric and electronic properties for creating novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing biphenyl or methoxy-substituted aromatic systems.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile organoboron partner for palladium-catalyzed carbon-carbon bond formation, enabling the creation of complex biaryl structures prevalent in medicinal chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications.
• Organic Electronic Materials: Acts as a building block for the development of organic light-emitting diodes (OLEDs), semiconductors, and other advanced functional materials.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probes: Useful for the development of molecular probes and sensors due to its specific reactivity profile.

Basic Information

Product Name	Boronic Acid, B-(5-Methoxy[1,1'-Biphenyl]-3-Yl)-
CAS No.	1111181-69-1
Molecular Formula	C19H17BO3
Molecular Weight	304.15 g/mol
Synonyms	[5-Methoxy-3-biphenylyl]boronic acid; (5'-Methoxy[1,1'-biphenyl]-3-yl)boronic acid; 3-(5-Methoxybiphenyl)boronic acid; B-(5-Methoxy[1,1'-biphenyl]-3-yl)boronic acid; 5-Methoxy-3-biphenylboronic acid; 3-Biphenylboronic acid, 5'-methoxy-; Boronic acid, B-[5-methoxy[1,1'-biphenyl]-3-yl]- (9CI)
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(5-Methoxy[1,1'-Biphenyl]-3-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.