Description

(11Bs)-(-)-4,4-Dibutyl-2,6-Bis[3,5-Bis(trifluoromethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepinium Bromide (S-Maruoka Catalyst p-Nb) is a highly advanced, chiral, cationic organocatalyst belonging to the Maruoka catalyst family. This compound is specifically engineered to deliver exceptional enantioselectivity and catalytic activity in asymmetric synthesis, a cornerstone of modern pharmaceutical and fine chemical manufacturing. It is an indispensable tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control for creating novel, high-value molecules.

Application

• Asymmetric Phase-Transfer Catalysis (PTC): Enables enantioselective alkylation, Michael addition, and Mannich reactions under mild conditions.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• Agrochemical Development: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Facilitates the production of specialty chemicals, flavors, and fragrances with specific stereochemistry.
• Academic & Industrial R&D: A key reagent for methodological development in organic synthesis and catalysis research.
• Material Science: Potential applications in creating chiral polymers or frameworks with unique optical properties.

Basic Information

Product Name	(11Bs)-(-)-4,4-Dibutyl-2,6-Bis[3,5-Bis(trifluoromethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepinium Bromide (S-Maruoka Catalyst p-Nb)
CAS No.	1110813-90-5
Molecular Formula	C54H40BrF12P
Molecular Weight	1043.75 g/mol
Synonyms	S-Maruoka Catalyst p-Nb; Maruoka Catalyst p-Nb Bromide; (S)-4,4-Dibutyl-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepinium Bromide; (S)-p-Nb Catalyst; (S)-Maruoka's PTC Catalyst p-Nb; (S)-Quaternary Ammonium Salt Catalyst p-Nb; Bromide salt of S-Maruoka catalyst; Asymmetric Phase Transfer Catalyst p-Nb
EINECS	Contact for details

Quality Control

Every batch of our S-Maruoka Catalyst p-Nb is manufactured and tested under stringent quality protocols to ensure consistent high performance and purity for critical asymmetric synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as enantiomeric excess, assay, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing under an inert gas in a sealed container at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.