Description

5-[(S)-(-)-2-(Methoxymethyl)Pyrrolidino]Sulfonylisatin is a high-purity, advanced pharmaceutical intermediate featuring a chiral pyrrolidine scaffold. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including protease inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its chiral center and functionalized isatin core.
• Protease Inhibitor Development: Serves as a key scaffold in the design and synthesis of potential inhibitors for various protease enzymes.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological mechanisms and target identification.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective synthetic routes to access enantiomerically pure compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	5-[(S)-(-)-2-(Methoxymethyl)Pyrrolidino]Sulfonylisatin
CAS No.	1110670-49-9
Molecular Formula	C15H18N2O5S
Molecular Weight	338.38 g/mol
Synonyms	(S)-5-[(2-(Methoxymethyl)pyrrolidin-1-yl)sulfonyl]isatin; 5-[(2S)-2-(Methoxymethyl)-1-pyrrolidinyl]sulfonyl-1H-indole-2,3-dione; (S)-5-((2-(Methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione; 5-((S)-2-(Methoxymethyl)pyrrolidine-1-sulfonyl)isatin; CAS 1110670-49-9; Sulfonylisatin derivative; Chiral pyrrolidino sulfonylisatin
EINECS	Contact for details

Quality Control

Our 5-[(S)-(-)-2-(Methoxymethyl)Pyrrolidino]Sulfonylisatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.