Description

trans-3-Oxabicyclo[3.1.0]Hexane-6-Acetic Acid is a high-purity, specialized bicyclic oxetane derivative with an acetic acid functional group, serving as a critical chiral building block and synthetic intermediate. Its unique constrained oxabicyclo[3.1.0]hexane scaffold is highly valued for introducing structural complexity and modulating physicochemical properties in advanced molecular design. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with enhanced biological activity and environmental profiles.
• Ligand and Catalyst Development: Precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Monomer or cross-linking agent for synthesizing polymers with unique thermal and mechanical properties derived from the strained oxetane ring.
• Chemical Biology Probe: Used to construct molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its rigid, three-dimensional structure.
• Flavor & Fragrance Ingredient Synthesis: Intermediate for creating complex, high-value aroma chemicals with unique olfactory characteristics.

Basic Information

Product Name	trans-3-Oxabicyclo[3.1.0]Hexane-6-Acetic Acid
CAS No.	1110650-68-4
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1R,5S,6r)-3-Oxabicyclo[3.1.0]hexane-6-acetic acid; (1R,5S,6r)-6-Acetic acid-3-oxabicyclo[3.1.0]hexane; trans-6-Carboxymethyl-3-oxabicyclo[3.1.0]hexane; Oxabicyclo[3.1.0]hexane-6-acetic acid, trans-; Bicyclo[3.1.0]hexane-6-acetic acid, 3-oxa-, (1R,5S,6r)-; 3-Oxabicyclo[3.1.0]hexane-6-acetic acid, (1R,5S,6r)-
EINECS	Contact for details

Quality Control

Our trans-3-Oxabicyclo[3.1.0]Hexane-6-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.