Description

5-Bromo-3,4-Dihydroisoquinolin-1(2H)-One is a high-value brominated isoquinoline derivative, a crucial synthetic intermediate in modern organic chemistry. Its core value lies in its versatile scaffold, which serves as a key building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug molecules targeting neurological disorders and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides, leveraging the biological activity of the isoquinoline core.
• Material Science: Serves as a monomer or precursor for creating specialized polymers and organic electronic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for library synthesis and structure-activity relationship (SAR) studies.
• Chemical Synthesis: Utilized in various organic transformations, including cross-coupling reactions and further functionalization of the isoquinoline ring system.

Basic Information

Product Name	5-Bromo-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1109230-25-2
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydroisoquinolin-1-one; 5-Bromo-3,4-dihydro-1(2H)-isoquinolinone; 5-Bromo-1-oxo-1,2,3,4-tetrahydroisoquinoline; 5-Bromotetrahydroisoquinolin-1-one; 5-Bromo-1,2,3,4-tetrahydroisoquinoline-1-one; 5-Bromo-3,4-dihydroisoquinolin-1(2H)-one; 5-Bromo-1,2,3,4-tetrahydro-1-isoquinolinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.