Description

Dimethyl Diglycolate-D4 is a deuterated derivative of dimethyl diglycolate, specifically designed for use as a stable isotope-labeled internal standard. This compound is essential for ensuring the accuracy and reliability of quantitative analytical methods, particularly in mass spectrometry. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors who require precise measurement and traceability in their analyses.

Application

• Quantitative Mass Spectrometry: Serves as a stable isotope-labeled internal standard for the accurate quantification of dimethyl diglycolate and related glycolate esters in complex matrices.
• Pharmaceutical Metabolism & Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of drug candidates and metabolites.
• Environmental Analysis: Enables precise tracking and measurement of glycolate-based compounds or degradation products in environmental samples.
• Agrochemical Research: Facilitates the study of the environmental fate, residue analysis, and metabolic pathways of herbicide intermediates.
• Analytical Method Development & Validation: Critical for developing robust LC-MS/MS and GC-MS methods that meet regulatory standards for specificity and accuracy.
• Biochemical Research: Acts as a tracer in studies of glyoxylate and glycolate metabolism within biological systems.

Basic Information

Product Name	Dimethyl Diglycolate-D4
CAS No.	1107650-54-3
Molecular Formula	C6H6D4O6
Molecular Weight	178.16 g/mol (approx.)
Synonyms	Dimethyl 2,2'-[1,2-Ethanediylbis(oxy)]bis[acetate-d2]; Bis(2-methoxy-2-oxoethyl) ether-d4; Diethylene glycol diacetate-d4 (dimethyl ester); Diglycolic acid dimethyl ester-d4; Deuterated dimethyl diglycolate; [2,2'-Oxybis(acetic acid-d2)] dimethyl ester; Dimethyl ether-d4 DEDO; Stable isotope-labeled dimethyl diglycolate.
EINECS	Contact for details

Quality Control

Every batch of Dimethyl Diglycolate-D4 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR (¹H, ²H) for isotopic enrichment confirmation and HPLC/GC-MS for chemical purity and identity. A detailed Certificate of Analysis (COA) specifying batch-specific data for purity, isotopic enrichment, and solvent residues is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Enrichment (Deuterium Content)	≥ 98 atom % D
Chemical Purity (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.