Description

1H-Indole, 7-Fluoro-5-Methoxy- is a high-purity, fluorinated indole derivative, a crucial advanced intermediate in modern organic synthesis. This compound matters for its role as a sophisticated building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical R&D and fine chemical manufacturers need it for constructing complex molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where the indole scaffold is privileged.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in serotonin receptor modulators and other CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated methoxyindole structure can confer specific biological activity and stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and specialty dyes.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) exploring new chemical entities.
• Fluorine Chemistry Studies: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorine substitution in heterocyclic systems.

Basic Information

Product Name	1H-Indole, 7-Fluoro-5-Methoxy-
CAS No.	1106942-47-5
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	7-Fluoro-5-methoxy-1H-indole; 5-Methoxy-7-fluoroindole; 7-Fluoro-5-methoxyindole; 1H-Indole, 7-fluoro-5-methoxy-; 7-Fluoro-5-methoxytryptamine precursor; 5-Methoxy-7-fluoro-1H-indole; 7-Fluoro-5-methoxy-1H-indole (CAS 1106942-47-5)
EINECS	Contact for details

Quality Control

Our 1H-Indole, 7-Fluoro-5-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.