Description

3-Chloro-7,8-Dihydroisoquinolin-5(6H)-One is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure, featuring a chloro-substituent and a ketone group, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or charge-transport materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, dyes, and complex fragrance molecules.

Basic Information

Item	Detail
Product Name	3-Chloro-7,8-Dihydroisoquinolin-5(6H)-One
CAS No.	1105662-39-2
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydroisoquinolin-5-one; 3-Chloro-7,8-dihydro-5(6H)-isoquinolinone; 3-Chloro-5,6,7,8-tetrahydro-1-isoquinolinone; 3-Chloro-5-oxo-5,6,7,8-tetrahydroisoquinoline; 1105662-39-2; 3-Chloro-5,6,7,8-tetrahydroisoquinolin-5-one; 3-Chloro-7,8-dihydroisoquinolin-5(6H)-one
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-7,8-Dihydroisoquinolin-5(6H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.