Description

tert-Butyl (2-Methyl-1H-Indol-5-Yl)Methylcarbamate is a specialized organic compound belonging to the indole carbamate class, serving as a crucial building block in advanced chemical synthesis. This high-purity intermediate is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides that require specific indole-based structures for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED displays and lighting due to its indole core.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation and Probe Chemistry: The carbamate protecting group makes it useful for constructing biochemical probes and antibody-drug conjugates (ADCs).
• Academic and Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	tert-Butyl (2-Methyl-1H-Indol-5-Yl)Methylcarbamate
CAS No.	1105193-63-2
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	5-[[(tert-Butoxycarbonyl)amino]methyl]-2-methyl-1H-indole; 1H-Indole-5-methanamine, N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-; tert-Butyl N-[(2-methyl-1H-indol-5-yl)methyl]carbamate; Boc-5-(aminomethyl)-2-methylindole; N-Boc-2-methyl-5-indolylmethylamine; (2-Methyl-1H-indol-5-yl)methyl-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Every batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.