Description

2-{[4-(Methylsulfonyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct thiazole-carboxylic acid core functionalized with a methylsulfonylphenylamino group. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and anti-inflammatory research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop and scale up next-generation small molecule drugs, where its precise structure enables specific biological interactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Biochemical Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for developing new APIs with potential anti-cancer or anti-inflammatory properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploring new chemical entities and their biological mechanisms.

Basic Information

Product Name	2-{[4-(Methylsulfonyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid
CAS No.	1105191-87-4
Molecular Formula	C11H10N2O4S2
Molecular Weight	298.34 g/mol
Synonyms	4-Carboxy-2-[(4-methylsulfonylphenyl)amino]thiazole; 2-[(4-Methanesulfonylphenyl)amino]-1,3-thiazole-4-carboxylic acid; 2-((4-(Methylsulfonyl)phenyl)amino)thiazole-4-carboxylic acid; 2-[(4-Methylsulfonylphenyl)amino]-4-thiazolecarboxylic acid; 1105191-87-4; 2-[(4-Methanesulphonylphenyl)amino]-1,3-thiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-{[4-(Methylsulfonyl)Phenyl]Amino}-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.