Description

Acetyleneboronic Acid Mida Ester, Acetynylboronic Acid Mida Ester, Ethyneboronic Acid Mida Ester is a highly versatile and valuable organoboron building block, specifically designed for robust Suzuki-Miyaura cross-coupling reactions. Its core value lies in the MIDA (N-methyliminodiacetic acid) boronate ester group, which provides exceptional stability to air and moisture while remaining readily reactive under standard cross-coupling conditions. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and advanced materials science who require reliable, shelf-stable reagents for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex drug candidates, particularly those requiring sp-sp2 carbon-carbon bond formation.
• Agrochemical Research & Development: Used in the synthesis of novel active ingredients for crop protection products.
• Material Science & Polymer Chemistry: Enables the incorporation of acetylene units into conjugated polymers and organic electronic materials.
• Chemical Biology & Probe Development: Serves as a stable handle for bioorthogonal labeling and the synthesis of molecular probes.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands and organometallic catalysts.
• Academic & Industrial R&D: A fundamental reagent for methodology development in organic synthesis and catalysis research.

Basic Information

Item	Details
Product Name	Acetyleneboronic Acid Mida Ester
CAS No.	1104637-53-7
Molecular Formula	C9H12BNO4
Molecular Weight	209.01 g/mol
Synonyms	Acetynylboronic Acid Mida Ester; Ethyneboronic Acid Mida Ester; (Ethynyl)boronic acid MIDA ester; 2-(Ethynyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methyliminodiacetic acid boronate ester; MIDA Boronate Ester of Ethynylboronic Acid; 1-Ethynyl-1,3,2-benzodioxaborole MIDA ester; Boronic acid, ethynyl-, MIDA ester; N-Methyliminodiacetic acid (MIDA) ethynylboronate
EINECS	Contact for details

Quality Control

Our Acetyleneboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.