Description

2-Bromo-5-(tert-Butyl)-1,3-Diiodobenzene is a highly functionalized, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic positioning of three distinct halogen atoms (bromine and two iodines) and a bulky tert-butyl group, which enables selective cross-coupling reactions and the construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing sterically hindered, poly-substituted benzene cores found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the halogen atoms allow for sequential functionalization to optimize biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis, leveraging the reactivity of the halogens.
• Organic Electronic Materials: Acts as a building block for π-conjugated systems, such as organic semiconductors, OLEDs, and photovoltaic materials, where the halogens facilitate metal-catalyzed coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Research & Development: A versatile scaffold in academic and industrial R&D for exploring new chemical reactions, synthesizing libraries of compounds for screening, and developing novel synthetic methodologies.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to create polymers with specific halogen functionalities for further modification or unique material properties.

Basic Information

Product Name	2-Bromo-5-(tert-Butyl)-1,3-Diiodobenzene
CAS No.	1104253-51-1
Molecular Formula	C10H11BrI2
Molecular Weight	464.91 g/mol
Synonyms	1,3-Diiodo-2-bromo-5-tert-butylbenzene; 2-Bromo-5-tert-butyl-1,3-diiodobenzene; 5-tert-Butyl-2-bromo-1,3-diiodobenzene; 1-Bromo-3,5-diiodo-4-tert-butylbenzene (alternative numbering); Benzene, 2-bromo-5-(1,1-dimethylethyl)-1,3-diiodo-; Tert-Butyl Diiodobromobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(tert-Butyl)-1,3-Diiodobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.