Description

5-tert-Butyl 3-Ethyl 2-Amino-6,7-Dihydrothieno[3,2-C]Pyridine-3,5(4H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1101856-88-5. This compound is a critical building block in modern medicinal chemistry, valued for its complex fused-ring heterocyclic structure that serves as a core scaffold in drug discovery. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.

Application

This specialized intermediate is designed for high-value synthesis applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: Serving as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) with potential neurological or cardiovascular activity.
• Drug Discovery & Medicinal Chemistry: Acting as a privileged scaffold for constructing compound libraries and optimizing lead molecules in research and development pipelines.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.

Basic Information

Product Name	5-tert-Butyl 3-Ethyl 2-Amino-6,7-Dihydrothieno[3,2-C]Pyridine-3,5(4H)-Dicarboxylate
CAS No.	1101856-88-5
Molecular Formula	C17H26N2O4S
Molecular Weight	354.47 g/mol
Synonyms	5-tert-Butyl 3-ethyl 2-amino-4,7-dihydro-5H-thieno[3,2-c]pyridine-3,5-dicarboxylate; 2-Amino-5-tert-butoxycarbonyl-3-ethoxycarbonyl-4,7-dihydro-5H-thieno[3,2-c]pyridine; Ethyl 2-amino-5-[(tert-butoxy)carbonyl]-4,7-dihydro-5H-thieno[3,2-c]pyridine-3-carboxylate; 5H-Thieno[3,2-c]pyridine-3,5-dicarboxylic acid, 2-amino-4,7-dihydro-, 3-ethyl 5-(1,1-dimethylethyl) ester; CAS 1101856-88-5.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with quality standards suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and should be stored in a cool, dry place, ideally at 2-8°C for long-term stability. For extended storage, consider desiccation or storage under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.