Description

5-Methylpyrazine-2-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyrazine cores for drug discovery and development.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures for enhanced efficacy.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel palladium catalyst ligands to optimize cross-coupling reaction conditions.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Details
Product Name	5-Methylpyrazine-2-Boronic Acid Pinacol Ester
CAS No.	1101205-24-6
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	5-Methyl-2-pyrazineboronic acid pinacol ester; (5-Methylpyrazin-2-yl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylpyrazine; 5-Methylpyrazine-2-boronic acid neopentyl glycol ester (common name); Pinacol 5-Methylpyrazine-2-boronates; 5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine
EINECS	Contact for details

Quality Control

Every batch of 5-Methylpyrazine-2-Boronic Acid Pinacol Ester is manufactured and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR (1H, 13C, and 11B), and GC/MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.