Description

2-Ethyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1101199-16-9. This compound is critical for the synthesis of complex molecules, offering a key chiral building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a crucial building block for constructing complex heterocyclic scaffolds in drug discovery programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals and complex organic molecules.
• Biochemical Research: Potential application in the development of enzyme inhibitors or receptor ligands due to its tetrahydroisoquinoline core structure.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential drug candidates during clinical development phases.

Basic Information

Product Name	2-Ethyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	1101199-16-9
Molecular Formula	C13H17NO2·HCl
Molecular Weight	255.74 g/mol
Synonyms	2-Ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; 2-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid HCl; 3-Carboxy-2-ethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 2-Ethyl-3-carboxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; (3S)-2-Ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride (for enantiopure form); ETIQ-3-COOH·HCl; 1101199-16-9
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment where applicable, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.