Description

4-Fluorobenzamide-D4 is a deuterium-labeled analog of 4-fluorobenzamide, a key intermediate in organic synthesis and analytical chemistry. This high-purity, isotopically enriched compound is essential for creating internal standards in mass spectrometry, enabling precise quantification and metabolic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical instrumentation industries for drug development, environmental analysis, and advanced material science.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference standard in quantitative bioanalytical methods for pharmacokinetic and metabolomic studies.
• Pharmaceutical Research: Used as a deuterated building block in the synthesis of novel drug candidates, facilitating metabolic pathway tracing and stability testing.
• Metabolic Pathway Investigation: Enables the detailed study of drug metabolism and disposition through Deuterium Isotope Effect (DIE) studies.
• Agrochemical Analysis: Employed in the development of analytical methods for detecting and quantifying fluorinated pesticide residues and their metabolites.
• Environmental Monitoring: Acts as a standard in assays designed to trace fluorinated organic compounds in environmental samples.
• Chemical Synthesis Intermediate: Provides a labeled core structure for synthesizing more complex deuterated molecules for various R&D applications.

Basic Information

Product Name	4-Fluorobenzamide-D4
CAS No.	1100750-65-9
Molecular Formula	C7H2D4FNO
Molecular Weight	143.16 g/mol
Synonyms	4-Fluoro-D4-benzamide; p-Fluorobenzamide-D4; Benzamide, 4-fluoro-2,3,5,6-tetradeuterio-; 2,3,5,6-Tetradeuterio-4-fluorobenzamide; Deuterated 4-Fluorobenzamide; [2H4]-4-Fluorobenzamide; 4-Fluorobenzamide (phenyl-D4); 4-FBA-D4
EINECS	Contact for details

Quality Control

Every batch of 4-Fluorobenzamide-D4 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuteration level and chemical purity, ensuring compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, purity, isotopic enrichment, and impurities is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuteration Degree (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.