Description

5-Fluoro-1-Benzothiophene-2-Carboxamide is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, where its benzothiophene core and fluorine substituent impart unique biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated benzothiophene scaffold.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	5-Fluoro-1-Benzothiophene-2-Carboxamide
CAS No.	1098356-12-7
Molecular Formula	C9H6FNO1S
Molecular Weight	195.21 g/mol
Synonyms	5-Fluorobenzo[b]thiophene-2-carboxamide; 1-Benzothiophene-2-carboxamide, 5-fluoro-; 5-Fluoro-1-benzothiophene-2-carboxylic acid amide; 5-Fluoro-benzo[b]thiophene-2-carboxamide; 5-F-BT-2-CA; 1098356-12-7
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Benzothiophene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.