Description

1H-1,2,4-Triazole-3-Thiol, 5-Cyclobutyl- is a specialized heterocyclic building block featuring a triazole core functionalized with a thiol group and a cyclobutyl substituent. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought by research institutions and industrial manufacturers engaged in medicinal chemistry, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the triazole-thiol moiety can act as a pharmacophore or metal-binding group.
• Agrochemical Research: Used in developing new generations of fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis in Catalysis: Serves as a starting material for creating specialized ligands used in transition metal catalysis for complex organic transformations.
• Material Science Precursor: Employed in the research and development of advanced polymers or functional materials with specific chemical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	1H-1,2,4-Triazole-3-Thiol, 5-Cyclobutyl-
CAS No.	1097794-73-4
Molecular Formula	C6H9N3S
Molecular Weight	155.22 g/mol
Synonyms	5-Cyclobutyl-1H-1,2,4-triazole-3-thiol; 5-Cyclobutyl-3-mercapto-1,2,4-triazole; 3-Mercapto-5-cyclobutyl-1,2,4-triazole; 5-Cyclobutyl-1,2,4-triazole-3-thiol; Cyclobutyl-substituted triazolethiol; 1,2,4-Triazole-3-thiol, 5-cyclobutyl-; 3-Thiol-5-cyclobutyl-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our production of 1H-1,2,4-Triazole-3-Thiol, 5-Cyclobutyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.